My research focuses on developing and applying of state-of-the-art mass spectrometry and proteomics to accurately quantify the temporal changes in the proteome, and to identify the potential diagnostic biomarkers and drug targets for the treatment of diseases. Specifically, I am interested in the following aspects:
Characterization of innate immunity signaling pathway by stable isotope dilution-selected reaction monitoring mass spectrometry (SID-SRM-MS)
Biomarker discovery and verification.
Quantitative proteomics and phosphoproteomics.
Proteomic analysis of other protein post-translational modifications