My research centers on application and/or development of image processing and magnetic resonance imaging (MRI) techniques for a variety of biomedical focus areas:
1. Psychiatry:
Research is focused on improving automated methods of brain tissue identification and volume measurement using magnetic resonance images in the context of a study of depression in aging. Similar work is ongoing in bipolar disorder.
2. Oncology:
Research efforts center on how to best quantitate MRI-based diffusion and perfusion parameters and apply them to predicting the course and outcome of cancer therapy. Current efforts involve developing robust algorithms for removing distortion from echo-planar MR diffusion images and producing high resolution MR diffusion images on our research 3 Tesla MR imaging system (Center for Advanced MR Development, CAMRD)
3. Pediatric Neurology/Psychiatry:
I am collaborating with researchers at Duke to use MRI methods to evaluate childhood epilepsy, addictions, trauma and abuse. Some of these involve multi-site studies
