Research interests in the molecular markers of prognosis in pediatric brain tumors, and neurodegenerative diseases such as Alzheimer`s, Lewy body dementia, ALS and Parkinson`s disease. He is also Director of the Neuropathology Brain Bank and Case Editor for Brain Pathology, the journal of the International Society of Neuropathology. The Case of the Month is posted on the web (http://brainpathology.upmc.edu) and three cases are published quarterly. The pediatric brain tumor research is conducted with Children`s Hospital of Pittsburgh in collaboration with Dr. Ian Pollack, a pediatric neurosurgeon and the Children`s Cancer Group (CCG) and Pedatric Brain Tumor Consortium As the diagnostic neuropathologist for the Neuropathology Core of the Alzheimer`s Disease Research Consortium (ADRC) and head of the Neuropathology brain bank, Dr. Hamilton also collaborates with numerous dementia researchers.