Physiology, pathophysiology and management of swallowing and its disorders. Evaluation of novel techniques to assess the biomechanics of the pharyngeal swallow (combined manometry & radiography, high resolution manometry, intraluminal impedance, scintigraphy). Novel approaches to evaluation and treatment of pharyngeal dysphagia. Predictors of outcome and implications for radiation dosimetry in head and neck cancer patients undergoing radiotherapy. Therapeutic approaches to and novel biomechanical measures predicting outcome in oesophageal dysphagia due to achalasia, eosinophilic oesophagitis. Mechanisms of phonation and quality of oesophageal speech in patients following total laryngectomy. Studies of oesophageal afferent nerve function and reflexes and how these impact reflux disease and its complications including regurgitation and respiratory complications. Pathophysiology of oesophago-pharyngeal regurgitation. Pathophysiology of functional heartburn. Pathophysiology of constipation syndromes. Novel therapeutic approach to treatment of severe constipation (eg sacral nerve stimulation).