My work in immunology and molecular virology focused on the mechanisms by which chronic viruses modulate the host immune response, and how these interactions contribute to lymphoproliferative disorders and other chronic diseases. Current research focuses on the molecular, genetic, and immunologic mechanisms that underlie leukemia and lymphoma development. Specifically, which microenvironmental interactions influence the development and persistence of these diseases. Other interests include the role of chronic viruses in lymphoma development, and the genetic characteristics that influence diagnosis and treatment of pre-myeloid leukemias or myelodysplastic syndromes.