Dr. Hu’s core research interests are to explore the immune-related mechanisms of ischemic stroke and neurodegenerations and to develop immunotherapies to treat these conditions. Her research directions include 1) exploring the protective effect of regulatory T cells (Tregs) in models of stroke, and 2) exploring “recovery-enhancing drugs” that not only promote gray matter integrity but also enhance white matter recovery after stroke, and 3) characterize microglia/macrophage polarization after stroke and identify the molecular switches in microglia/macrophages that control phenotypic change.