Postdoctoral Position for Novel Therapeutic Drug Identification at The University of Alabama at Birmingham
We are recruiting a self-motivated postdoctoral researcher to work on the funded project of identifying novel therapeutic drug candidates for target proteins involved in Alzheimer's disease. The project aims to screen and identify the novel compounds with desired binding activity for protein targets, ability to activate relevant cellular responses, and synergy with other binding compounds for wanted cellular activities. The identified top drug candidates will be further investigated with in vivo studies and dish-based clinical trials using iPSC technology for the therapeutic outcome studies. We also investigate protein-protein interactions and small molecule-target protein interactions and how these are changed by disease-associated genetic variants to gain insights for the mechanisms of action in Alzheimer's disease. The developed approaches could be also used for novel therapeutic drug identification in other diseases.
Candidates should have strong molecular and cell biology and animal handling skills as evidenced by first-author publication(s) in quality peer-reviewed journals. Previous research experience in iPSC technology is desirable. Candidate should be able to work with a high degree of independence and with good team spirit.
The candidate could gain additional computational biology training, if interested.
Interested candidates, please contact Dr. Yuhua Song, Professor of Biomedical Engineering at The University of Alabama at Birmingham by email: yhsong@uab.edu and include your CV and transcripts in the email.
The University of Alabama at Birmingham (UAB) is a research university and academic health center that discovers, teaches, and applies knowledge for the intellectual, cultural, social, and economic benefit of Birmingham, the state, and beyond. UAB is internationally renowned for its intensely collaborative culture that has — for more than five decades — produced breakthroughs in education, health care, research, and service. UAB was ranked #1 in the United States, and in the top 10 worldwide, in the Times Higher Education World University Rankings, 2018 Young University Rankings.
