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Job ID: 156598

Graduate Students
Hopitla Maisonneuve-Rosemont

Date Posted Mar. 27, 2021
Title Graduate Students
University Hopitla Maisonneuve-Rosemont
Montreal, QC, Canada
Department CRHMR
Application Deadline May 1, 2021
Position Start Date Availble immediately
  • Graduate Student
  • Immunology & Infectious Diseases
    Biomedical Engineering/Biomedical Sciences
    Biochemistry & Cellular Biology

Applications are invited for Ph.D. positions to study the mechanism of tissue regeneration/re-modeling properties of mesenchymal stem cells (MSCs) and T cell development/function using molecular, cellular and biochemical techniques at the Center for Research Hopital Maisonneuve-Rosemont (CRHMR).
Using rat model of open angle glaucoma, we previously showed that MSCs grown under specific conditions accelerate tissue repair and corrects glaucoma like conditions (Manuguerra-Gagnon R etal Stem Cell 2013). We wish to extend these studies and aim to identify critical molecules and immune cell population involved in mediating wound healing capacity of MSCs.
For the T cell development/function project we use gene knockout and transgenic mouse model to study CD4/CD8 lineage choice. We recently showed that Thpok transcription factor differentially influences CD4 choice of MHCII- and MHCI-specific thymocytes (Zeidan N etal J. Immunology 2019). These models will be employed to further dissect T cell development/function with particular emphasis translating research into clinically relevant immune disorders or developing cancer immunotherapy.
Third project involves isolation and functional characterization of minor histocompatibility antigen specific T cells for improving immunotherapy for hematologic cancers.

Applicants must have Master degree in immunology/biology with strong GPA and good knowledge of molecular, cellular biology and biochemical techniques. For T cell development background in immunology is must. You are expected to have strong work ethics, motivation and organizational skill and be a team player. Successful candidates will have opportunities to present their work in national and international meetings, and are required to participate in institutional student and invited speaker seminars. Functional knowledge of French is desired.

How to apply:
Interested applicants should send CV describing GPA, academic/research achievements and names of three references to

  • CRHMR is an equal opportunity employer and prohibits discrimination on any basis.

Please reference in your cover letter when
applying for or inquiring about this job announcement.

Contact Information

  • Vibhuti Dave
    Hopitla Maisonneuve-Rosemont
    5415 Blvd Assomption
    Montreal, QC H1T 2M4


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