Dr. Eko's research focuses on vaccine development, vaccine delivery systems, animal models, evaluation and characterization of vaccine-induced innate and adaptive immune responses including the mechanisms by which protective immunity is generated. Dr. Eko developed the Vibrio cholerae ghost (VCG) vaccine and drug delivery platform. VCG are genetically derived, self-adjuvanting vibrio cell envelopes that maintain the native conformation of co-delivered antigens.